2019
Nagashima R, Kosai H, Masuo M, Izumiyama K, Noshikawaji T, Morimoto M, Kumaki S, Miyazaki Y, Motohashi H, Yamamoto M, Tanaka N.
Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response.
J Immunol. 2019 Mar 1;202(5):1331-1339. doi: 10.4049/jimmunol.1801180.
2018
Tsukita Y, Okazaki T, Ebihara S, Komatsu R, Nihei M, Kobayashi M, Hirano T, Sugiura H, Tamada T, Tanaka N, Sato Y, Yagita H, Ichinose M.
Beneficial effects of sunitinib on tumor microenvironment and immunotherapy targeting death receptor5.
Oncoimmunology. 2018 Nov 13;8(2):e1543526. doi: 10.1080/2162402X.2018.1543526.
Suga J, Izumiyama K, Tanaka N, Saji S.
Estradiol promotes rapid degradation of HER3 in ER-positive breast cancer cell line MCF-7.
Biochem Biophys Rep. 2018 Oct 26;16:103-109. doi: 10.1016/j.bbrep.2018.10.008
2017
Sato T, Morita M, Tanaka R, Inoue U, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y and Tanuma N
Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells.
Oncologist Letters 2017 14(6): 6863–6868. doi: 10.3892/ol.2017.7098.
Nasu K, Yamaguchi K, Takanashi T, Tamai K, Sato I, Ine S, Sasaki O, Satoh K, Tanaka N, Tanaka Y, Fukushima T, Harigae H, Sugamura K.
“Crucial role of carbonic anhydrase IX in tumorigenicity of xenotransplanted adult T-cell leukemia-derived cells.”
Cancer Science 108:435-443 (2017) doi: 10.1111/cas.13163.12, 61.
Willén K, Edgar JR, Hasegawa T, Tanaka N, Futter CE, Gouras GK.
“Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.”
Molecular Neurodegeneration 12, 61 (2017) doi: 10.1186/s13024-017-0203-y.
Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y, Tanuma N.
“Ex vivo model of non‑small cell lung cancer using mouse lung epithelial cells”
Oncology Letters 14, 6863-6868 (2017) doi: https://doi.org/10.3892/ol.2017.7098.
2016
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M & Tanaka N
“ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways”
Scientific Reports 6, 24997 (2016) doi:10.1038/srep24997
Watanabe K, Fukuhara T, Tsukita Y, Morita M, Suzuki A, Tanaka N, Terasaki H, Nukiwa T, Maemondo M.
“EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method”
Can Respir J. 2016;2016:5297329. doi: 10.1155/2016/5297329.
Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
“Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription”
Nature Communications. 2016 7:11624. doi: 10.1038/ncomms11624.
Mochizuki M. Tamai K. Imai T. Sugawara S. Ogama N. Nakamura M. Matsuura K. Yamaguchi K. Satoh K. Sato I. Motohashi H. Sugamura, K. & Tanaka, N.
“CD271 regulates the proliferation and motility of hypopharyngeal cancer cells”
Scientific Reports 6, Article number: 30707. (2016) doi: 10.1038/srep30707
Maejima R, Tamai K, Shiroki T, Yokoyama M, Shibuya R, Nakamura M, Yamaguchi K, Abue M, Oikawa T, Noguchi T, Miura K, Fujiya T, Sato I, Iijima K, Shimosegawa T, Tanaka N, Satoh K.
“Enhanced expression of semaphorin 3E is involved in the gastric cancer development”
Int J Oncol. 2016;49:887-94. doi: 10.3892/ijo.2016.3593.
Yamaguchi K, Takanashi T, Nasu K, Tamai K, Mochizuki M, Satoh I, Ine S, Sasaki O, Satoh K, Tanaka N, Harigae H. & Sugamura K.
“Xenotransplantation elicits salient tumorigenicity of adult T-cell leukemia-derived cells via aberrant AKT activation”
Cancer Science. 107, 638-643, 2016. doi: 10.1111/cas.12921.
Mizuguchi M, Sasaki Y, Hara T, Higuchi M, Tanaka Y, Funato N, Tanaka N, Fujii M, Nakamura M.
“Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax”
PLoS One, 11:e0148217(2016).
2014
Nagata T, Murata K, Murata R, Sun SL, Saito Y, Yamaga S, Tanaka N, Tamai K, Moriya K, Kasai N, Sugamura K & Ishii N.
“Hepatocyte growth factor regulated tyrosine kinase substrate in the peripheral development and function of B-cells”.
Biochem Biophys Res Commun. 2014;443:351-6. doi: 10.1016/j.bbrc.2013.11.029.
Tamai K, Nakamura M, Mizuma M, Mochizuki M, Yokoyama M, Endo H, Yamaguchi K, Nakagawa T, Shiina M, Unno M, Muramoto K, Sato I, Satoh K, Sugamura K & Tanaka N. “Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinoma”
Cancer Science 105, 667-674 (2014)
Watanuki Z, Kosai H, Osanai N, Ogama N, Mochizuki M, Tamai K, Yamaguchi K, Satoh K, Fukuhara T, Maemondo M, Ichinose M, Nukiwa T, Tanaka N.
“Synergistic cytotoxicity of afatinib and cetuximab against EGFR T790M involves Rab11-dependent EGFR recycling”
Biochem Biophy Res Commun. 455, 269-276 (2014)
Publications
Grants
2019 科研費 基盤研究(C) 代表 小鎌 直子
2019 科研費 若手(B) 代表 長島 隆一
2018 科研費 基盤研究(B) 代表 田中 伸幸
2018 科研費 若手(B) 代表 西川路武人
2018 東北大学加齢医学研究所共同研究 田中 伸幸
2017 JST-CREST 細胞外微粒子に起因する生命現象の解明とその制御に向けた基盤技術の創出 福田チーム
分担 田中 伸幸
2017 内藤記念科学奨励金・研究助成 田中 伸幸
2017 東北大学加齢医学研究所共同研究 田中 伸幸
2017 科研費 若手(B) 代表 長島 隆一
2016 科研費 若手(B) 代表 泉山 慶子
2015 科研費 若手(B) 代表 小齋 仁美
2015 科研費 挑戦的萌芽 代表 田中 伸幸
2013 科研費 基盤研究(B) 代表 田中 伸幸
2011 JST-CREST 慢性炎症 分担 田中 伸幸
Awards
2017 北里医学会賞 長島 隆一
2017 北斗医学賞 西川路 武人
2014 東北大学大学院博士課程ブースター 大嶋 龍司